What is to be or become diseased, or as if diseased, with canker; to grow corrupt; to become venomous. Deceit and cankered malice. Dryden. As with age his body uglier grows, So his mind cankers. Shak called?

canker — To be or become diseased, or as if diseased, with canker; to grow corrupt; to become venomous. Deceit and cankered malice. Dryden. As with age his body uglier grows, So his mind cankers. Shak. (Webster's 1913.)

Sources