What is another word for "hardened"?

Roget's Thesaurus (1911) lists these synonyms for "hardened": agent, anaesthesia, anaesthetic, anaesthetize, and, benefit, benumb, blunt, callous, case, chloral, chloroform, clergy, coma, comatose, conscience, contrition, dead, die, dull, ether, exhilarating, game, gas, graceless, hard, harden, hardness, have, heart, hemiplegia, hide, impenitence, impenitent, impercipient, incorrigible, induration, influence, insensibility, insensible.