What is another word for "disadvantage"?

Roget's Thesaurus (1911) lists these synonyms for "disadvantage": accident, adversity, and, awry, back, bad, badness, balance, bale, bane, become, below, blow, bottom, box, bruise, buffet, calamity, candle, casualty, catastrophe, cause, come, commonalty, contract, contracted, cost, crying, damage, decrease, deficiency, deficient, demon, destruction, deterioration, devil, disadvantageous, disaster, disastrous, disservice.