What does "irksome" mean?

Irksome: Weary; vexed; uneasy. [Obs.] Let us therefore learn not to be irksome when God layeth his cross upon us. Latimer. -- Irksome, Wearisome, Tedious. These epithets describe things which give pain or disgust. Irksome is applied to something which disgusts by its nature or quality; as, an irksome task. Wearisome denotes that which wearies or wears us out by severe labor; as, wearisome employment. Tedious is applied to something which tires us out by the length of time occupied in its performance; as, a tedious speech. Wearisome nights are appointed to me. Job vii.